Coming from Medelco (retrofit of press and general mechanics), the Lyon company Medelpharm can boast more than 35 years of experience in the field of compression. Among other activities, the precision engineering company is the world leader in compaction simulators for R&D with Styl'One Evo and Styl'one Nano presses and provides innovative services for powder analysis and formulation support.
These unique presses on the market, stand out from the competition by a great ease of use coupled with a high level of measurement and data processing quality. Their 100% electromechanical design without hydraulics ensures performance and reproducibility of the measurements essential to meet the requirements of expert formulators.
Medelpharm has also developed two other major activities: the distribution of partner equipment and a laboratory activity in powder compression and grinding.
Its Medelpharm Distribution division announced earlier this year the signing of an agreement to exclusively represent the entire range of Korsch products and services in France and Belgium.
This offer of compressing presses completes Medelpharm's portfolio of products and brands in the treatment of powders. This contract supports the strategy of the Medelpharm Distribution division, which aims to dominate the powder compression market, from R&D to production in the fields of pharmacy, chemistry, food supplements and cosmetics.
Korsch has been developing and producing exclusively compressing machines and systems for regulation, tablet verification and data analysis since 1919. The German company offers a wide range of machines, from pilot equipment to high-capacity production rotaries. Renowned for their quality and technological advance, these presses cover the most varied applications up to 5-layer and double-core tablets. The equipment also meets the most advanced containment needs as well as specific applications such as very large tablets (battery, salt, laundry, ...).
The "Medelpharm Science Lab", based near Lyon, is open to demonstrations and tests of compression and grinding. Scientists at the Science Lab carry out custom studies, assist and train customers on equipment. They also accompany them on formulation optimization, powder characterization and particle engineering. "Our application laboratory offers several laboratory services such as powder and formulation characterization, formulation support, compression testing, troubleshooting and scaleup assistance",says Thomas Perron, Sales Manager Distribution.
The SME has aggregated services and equipment around needs. It can support a customer during the R&D phases, scale transposition phases and production phases thanks to its internal skills (in terms of compression simulators and expertise in powder compression) and the partners for whom it is an agent or distributor on French territory. For example, it works with laboratories for applications in formulation, granulation, coating and atomization of Xedev powder. And also offers Korsch R&D and production rotary presses, Quadro-Fitzpatrick grinding and sieving equipment, Granutools powder characterization equipment (flow, packed density and electrostatic charge can thus be characterized), LB Bohle production equipment (weighing systems, mixing handling, wet granulation, dry granulation and film coating for production) , systems for wet granulation, film coating, extrusion and atomization of Procept brand R&D powders, and Caleva R&D extruder and spheronizer.
"An industrialist in the field of pharmacy who has established his formulation to manufacture tablets can, for example, ask us to study the compressibility of his formulation. The characteristics of the powders will be studied for all the components of the formulation in terms of morphogranulometry, flow, packed density and true density for example. The sensitivity to electrostatic charge can also be checked, before subjecting the powder to compression tests. On very low volumes of powders, our Styl'One Evo press is able to reproduce the linear movement speed of the punches of rotary production presses and thus allow to analyze the behavior of a powder at high production speeds. This is a key benefit for our customers in the development phase, explains Thomas Perron. Customers can also contact us to equip themselves with a production machine. Each customer request is unique. We are specialists in the compression and processing of powders: as soon as a customer has a problem related to the grinding or processing of powders, we can provide him with the expertise and equipment he needs with our teams or with the right partners. »
Medelpharm is mainly aimed at the pharmaceutical industry and to a lesser extent at chemical manufacturers, producers of food supplements and agri-food players. Cosmetics represent an increasingly important market. With a notable feature: a growing activity in the field of solid cosmetics, in dry form. "We feel a bottom blade concerning dry cosmetics, even if the volumes are not yet important, the manufacturers are not yet familiar with the fact of going to a specialized company like Medelpharm. More and more customers are asking us about our experience in the field of cosmetics," says Thomas Perron.
Styl'One Nano: an R&D tablet press for laboratory bench
Designed by Medelpharm, Styl'One Nano is an R&D tablet press for a laboratory bench with functions and features unprecedented in its class. Intended for scientific formulators, this equipment allows the formulation and characterization of powders in compression for the pharmaceutical, neutraceutical, chemical and agri-food industries.
Its advantage: to be able to offer native compression profiles described in the <1062>USP, profiles serving as a reference for the characterization of powders in compression (extended holding time, V-profiles, simple compression, pre-compression and main compression). The ability to reproduce main pre-compression and compression cycles just like rotary presses makes it a new tool on the market.
Compact and mobile, the Styl'One Nano machine is intended for table installation, a mobile roller base or a laminar flow cabin. With a cost studied to address the greatest number. Medelpharm aims to install a copy of the Styl'One Nano press in each laboratory developing compressed solid forms!